Health Canada PRCI Guiding Principles and Observations Blog Health Canada PRCI Guiding Principles and Observations Health Canada released guidance on 2019 年 3 月 12 日 pertaining to its Public Release of Clinical…Certara2019 年 9 月 16 日
A Population-based PBPK Model for the Prediction of Time-varying Bile Salt Disposition within GI Luminal Fluids – Toward a Mechanistic Model Poster A Population-based PBPK Model for the Prediction of Time-varying Bile Salt Disposition within GI Luminal Fluids – Toward a Mechanistic Model Danielle Pillsbury2019 年 9 月 4 日
Development of a PBPK model for topical lidocaine in order to predict systemic absorption in healthy volunteers, geriatrics and paediatrics Poster Development of a PBPK model for topical lidocaine in order to predict systemic absorption in healthy volunteers, geriatrics and paediatrics Danielle Pillsbury2019 年 9 月 4 日
Predicting the Concentration of PARP Inhibitors in Human Tumor Tissue Using PBPK Modeling Poster Predicting the Concentration of PARP Inhibitors in Human Tumor Tissue Using PBPK Modeling Danielle Pillsbury2019 年 9 月 4 日
Performance Verification and Application of a Cancer population for use in Physiologically Based Pharmacokinetic modelling Poster Performance Verification and Application of a Cancer population for use in Physiologically Based Pharmacokinetic modelling Danielle Pillsbury2019 年 9 月 4 日
Evaluation of maternal drug exposure following the administration of antenatal corticosteroids during late pregnancy using PBPK Modeling Poster Evaluation of maternal drug exposure following the administration of antenatal corticosteroids during late pregnancy using PBPK Modeling Danielle Pillsbury2019 年 9 月 4 日
INVESTIGATING THE IMPACT OF ENZYME CORRELATIONS ON INTER-INDIVIDUAL VARIABILITY IN PHARMACOKINETICS AND DRUG-DRUG INTERACTIONS Poster INVESTIGATING THE IMPACT OF ENZYME CORRELATIONS ON INTER-INDIVIDUAL VARIABILITY IN PHARMACOKINETICS AND DRUG-DRUG INTERACTIONS Danielle Pillsbury2019 年 9 月 4 日
Biokinetic and PBPK modelling to support the rotenone and strobilurin read across case studies (CS4) Poster Biokinetic and PBPK modelling to support the rotenone and strobilurin read across case studies (CS4) Danielle Pillsbury2019 年 9 月 4 日
Biokinetic and PBPK Modelling to Support Read-Across Assessment of Repeat Dose and Developmental and Reproductive Toxicity of Valproic Acid Analogues Poster Biokinetic and PBPK Modelling to Support Read-Across Assessment of Repeat Dose and Developmental and Reproductive Toxicity of Valproic Acid Analogues Danielle Pillsbury2019 年 9 月 4 日
Physiologically Based Pharmacokinetic/Pharmacodynamic model of gastrointestinal toxicity induced by 5-fluorouracil in mouse and translation to human Poster Physiologically Based Pharmacokinetic/Pharmacodynamic model of gastrointestinal toxicity induced by 5-fluorouracil in mouse and translation to human Danielle Pillsbury2019 年 9 月 4 日