Toward Unravelling the Mechanism of Cardiotoxicity of Citalopram: Utilization of Mechanistic Cardiac Electrophysiology Modelling with Simcyp Cardiac Safety Simulator (CSS) to Explore Various Hypotheses Poster Toward Unravelling the Mechanism of Cardiotoxicity of Citalopram: Utilization of Mechanistic Cardiac Electrophysiology Modelling with Simcyp Cardiac Safety Simulator (CSS) to Explore Various Hypotheses Danielle Pillsbury2019 年 8 月 28 日
Application of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for prediction of drug-drug interactions (DDIs) involving the JAK1/2 inhibitor Ruxolitinib in Caucasians and Japanese Poster Application of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for prediction of drug-drug interactions (DDIs) involving the JAK1/2 inhibitor Ruxolitinib in Caucasians and Japanese Danielle Pillsbury2019 年 8 月 28 日
Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model Poster Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model Danielle Pillsbury2019 年 8 月 28 日
APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS Poster APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS Danielle Pillsbury2019 年 8 月 28 日
Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis Poster Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis Danielle Pillsbury2019 年 8 月 28 日
Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example Poster Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example Danielle Pillsbury2019 年 8 月 28 日
APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ Poster APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ Danielle Pillsbury2019 年 8 月 28 日
THE RELATIONSHIP BETWEEN mRNA AND ACTIVITY FOLLOWING INDUCTION OF CYP3A4 AND CYP2B6 ACROSS A RANGE OF PROTOTYPICAL INDUCERS Poster THE RELATIONSHIP BETWEEN mRNA AND ACTIVITY FOLLOWING INDUCTION OF CYP3A4 AND CYP2B6 ACROSS A RANGE OF PROTOTYPICAL INDUCERS Danielle Pillsbury2019 年 8 月 28 日
DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION Poster DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION Danielle Pillsbury2019 年 8 月 23 日
Prediction of Prothrombin Time after Oral Administration of S-Warfarin in Different CYP2C9 Phenotypes in Asian and Caucasian populations using the Simcyp Simulator Poster Prediction of Prothrombin Time after Oral Administration of S-Warfarin in Different CYP2C9 Phenotypes in Asian and Caucasian populations using the Simcyp Simulator Danielle Pillsbury2019 年 8 月 23 日
