Applications of Linking PBPK and PD Models to Predict the Impact of Genotypic Variability, Formulation Differences, Differences in Target Binding Capacity and Target Site Drug Concentrations on Drug Responses and Variability Publication Applications of Linking PBPK and PD Models to Predict the Impact of Genotypic Variability, Formulation Differences, Differences in Target Binding Capacity and Target Site Drug Concentrations on Drug Responses and Variability This study aimed to demonstrate the added value of integrating prior in vitro data and…Danielle Pillsbury2014 年 11 月 26 日
Population Pharmacokinetics Analysis of Vigabatrin in Adults and Children with Epilepsy and Children with Infantile Spasms Publication Population Pharmacokinetics Analysis of Vigabatrin in Adults and Children with Epilepsy and Children with Infantile Spasms Vigabatrin is an inhibitor of γ-aminobutyric acid transaminase. The purpose of these analyses was to…Danielle Pillsbury2014 年 11 月 1 日