A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain Publication A Systems Pharmacology Perspective on the Clinical Development of Fatty Acid Amide Hydrolase Inhibitors for Pain The level of the endocannabinoid anandamide is controlled by fatty acid amide hydrolase (FAAH). In…Certara2014 年 1 月 15 日
Simplifying Deconvolution Knowledge Base Simplifying Deconvolution Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…Certara2014 年 1 月 13 日
The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study? 刊物 The IQ-CSRC Prospective Clinical Phase 1 Study: Can Early QT Assessment Using Exposure Response Analysis Replace the Thorough QT Study? A collaboration between the Consortium for Innovation and Quality in Pharmaceutical Development and the Cardiac…Certara2014 年 1 月 1 日
Incorporating Target Shedding into a Minimal PBPK-TMDD Model for Monoclonal Antibodies Publication Incorporating Target Shedding into a Minimal PBPK-TMDD Model for Monoclonal Antibodies Shedding of a pharmacological target from cells, giving rise to a soluble target that can also bind therapeutic proteins, is…Certara2014 年 1 月 1 日