Understanding Steady State Pharmacokinetics
“Steady state” is an important term in pharmacokinetics, but it can often seem a bit…
Certara2013 年 11 月 25 日
Absence of Pharmacokinetic Drug-drug Interaction of Pertuzumab with Trastuzumab and Docetaxel
Pertuzumab is a novel antihuman epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody. Combined…
Danielle Pillsbury2013 年 11 月 24 日
Phoenix WinNonlin: A State of the Art Software Tool for Pre-clinical PK and TK Analysis
Are you currently using Excel for PK/TK analysis? Phoenix WinNonlin streamlines analyses and generates all…
Danielle Pillsbury2013 年 11 月 21 日
What is Identifiability?
Developing models for pharmacokinetic or pharmacodynamic data requires creativity, patience, and hard work. Sometimes that…
Nathan Teuscher2013 年 11 月 18 日
Introduction to Population PK/PD Analysis Using Phoenix NLME
Phoenix NLME provides sophisticated algorithms and powerful and flexible data processing and modeling tools for…
Danielle Pillsbury2013 年 11 月 14 日
A Structure-guided Approach for Protein Pocket Modeling and Affinity Prediction
Binding affinity prediction is frequently addressed using computational models constructed solely with molecular structure and…
Danielle Pillsbury2013 年 11 月 9 日
Predicted Heart Rate Effect of Inhaled LABA PF-00610355 in Volunteers and COPD Patients
The aim of this study was to assess the cardiovascular effects of a new inhaled…
Danielle Pillsbury2013 年 11 月 1 日
