Simulations to Assess Phase 2 Non-inferiority Trials of Different Doses of Capecitabine in Combination with Docetaxel for Metastatic Breast Cancer Publication Simulations to Assess Phase 2 Non-inferiority Trials of Different Doses of Capecitabine in Combination with Docetaxel for Metastatic Breast Cancer A phase II trial in metastatic breast cancer (MBC) (NO16853) failed to show noninferiority (progression-free…Danielle Pillsbury2012 年 12 月 26 日
Calculating Urine PK Parameters BlogKnowledge Base Calculating Urine PK Parameters Pharmacokinetic analysis normally focuses on systemic exposure to a drug; however, much can be learned…Certara2012 年 12 月 6 日
Novel Biocompatible Disease Modifying Nanomedicine of VIP for Rheumatoid Arthritis Publication Novel Biocompatible Disease Modifying Nanomedicine of VIP for Rheumatoid Arthritis Despite advances in rheumatoid arthritis (RA) treatment, efficacious and safe disease-modifying therapy still represents an…Danielle Pillsbury2012 年 12 月 4 日
Application of PBPK Modeling to Predict Monoclonal Antibody Disposition in Plasma and Tissues in Mouse Models of Human Colorectal Cancer Publication Application of PBPK Modeling to Predict Monoclonal Antibody Disposition in Plasma and Tissues in Mouse Models of Human Colorectal Cancer This investigation evaluated the utility of a physiologically based pharmacokinetic (PBPK) model, which incorporates model…Danielle Pillsbury2012 年 12 月 1 日