Systems Pharmacology: Bridging Systems Biology and (PK/PD) Publication Systems Pharmacology: Bridging Systems Biology and (PK/PD) Mechanistic PKPD models are now advocated not only by academic and industrial researchers, but also…Danielle Pillsbury2011 年 5 月 11 日
Beyond Publication Bias Publication Beyond Publication Bias In drug development, clinical medicine, or health policy making, basing one's decisions on a selective…Danielle Pillsbury2011 年 5 月 1 日
The Development of UGT1A1 and 1A6 in the Pediatric Liver Publication The Development of UGT1A1 and 1A6 in the Pediatric Liver UDP-glucuronosyltransferases (UGTs) are critical for the metabolism and clearance of drugs, chemicals, and hormones. The…Danielle Pillsbury2011 年 5 月 1 日
Towards a Better Prediction of Peak Concentration, Volume of Distribution, and Half-life After Oral Drug Administration in Man, Using Allometry Publication Towards a Better Prediction of Peak Concentration, Volume of Distribution, and Half-life After Oral Drug Administration in Man, Using Allometry It is imperative that new drugs demonstrate adequate pharmacokinetic properties, allowing an optimal safety margin…Danielle Pillsbury2011 年 5 月 1 日
Pharmacokinetics of Clofarabine in Patients with High-risk Inherited Metabolic Disorders Undergoing Brain-sparing Hematopoietic Cell Transplantation Publication Pharmacokinetics of Clofarabine in Patients with High-risk Inherited Metabolic Disorders Undergoing Brain-sparing Hematopoietic Cell Transplantation Clofarabine, a newer purine analog with reduced central nervous system toxicity, may prove advantageous in…Danielle Pillsbury2011 年 5 月 1 日