Past Event
日期
October 18-20, 2022
Location
Boston, MA
2022 年基因治疗免疫原性
演讲嘉宾
We are excited to be presenting at this conference!
2022 年 10 月 19 日 | 12:30 PM ET
Biosimulation Model-informed Gene Therapy Development: Predicting Human Dose and Immunogenicity
Piet van der Graaf, PharmD, PhD
|高级副总裁，定量系统药理学部
Regulatory-ready IG simulator developed in consortium with eight pharmaceutical companies, now licensed by FDA | Applied to gene therapy for predicting human dose from pre-clinical data, to translational phases, and through clinical development | Case studies highlighting application to various modalities: AAV, mRNA and gene editing
